Polycystic kidney disease (PKD) is an inherited disease that replaces normal kidney tissue with fluid-filled cysts. As a result, over a 30- to 40-year period, the kidney stops working.

Symptoms of polycystic kidney disease include back and side pain, headache, urinary tract infections, and blood in the urine (hematuria).

There is no cure for PKD. Treatment includes antibiotics; medicines and surgery to control pain; and dialysis or kidney transplant to treat kidney failure.